Archive for the ‘Suboxone in a dissolvable film’ Category

Film Review: Suboxone

I had a chance to get more information about the new Suboxone film. I’ve decided I like it. It looks like one of those Listerine breath strips, and dissolves like one, too. When placed under the tongue, it dissolves faster than the tablets, but the taste is apparently about the same. The drug company’s representative brought me an inert (no active drug) film that’s supposed to taste exactly like the real thing. It was orange-flavored and bitterly sweet. While not terrible, it wasn’t tasty. But it was bearable. It dissolved very quickly, an advantage over the tablets.

I was concerned that my patients on 4mg or 12mg couldn’t use these films, as I heard they couldn’t be cut. But the drug company rep said the drug was evenly distributed on the film. Though the company’s official position was the film shouldn’t be cut into halves or fourths, it would probably work.  But she also reminded me that the drug company also says that about the tablets, but my patients use half-tabs frequently with no ill effects.

I don’t see any way the film can be snorted, though some creative and intelligent addict will probably find a way.

The films are contained in individual sealed pouches. Each pouch from the same box has the same number on it, meaning it would be very difficult to “fake” a pill (film) count if the doctor asked a patient to return to the pharmacy to make sure the appropriate amount of medication remains. If films from another box are substituted to make the count right, they will have different numbers. Very clever of the drug company. Oh, and the rep said the film would cost the same as the Suboxone tablet.

The film is available in pharmacies willing to stock it. If you are on Suboxone and want to try the film, be sure to ask your pharmacy to order it a few days before you think you will want to fill a prescription, to make sure they’ll have it.

I hope this delivery form is easier for patients and harder to divert or snort.

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New Form of Suboxone: Dissolving Film

Yesterday the FDA approved a new delivery system for the medication buprenorphine. Reckitt Benckiser, the drug company that makes the brands Suboxone (a combination pill of buprenorphine and naloxone) and Subutex (containing only buprenorphine), is now approved to manufacture and sell Suboxone in the form of a thin film that is placed under the tongue to be absorbed. According to early studies, patients think the film tastes better, dissolves more quickly, and is easier to use. I don’t yet have any information on the relative cost of this new film.

Since it was just approved, it’s not likely that a generic form of the film will be available for many years.

 This film of buprenorphine, the active ingredient, can’t be obtained as a generic, and it may be a few weeks before it appears in retail pharmacies.

 I’m hoping the sublingual (under the tongue) film will be harder to snort or inject, because there are reports of addicts misusing the Suboxone and Subutex tablets. And every addict misusing the name brands or the generic of buprenorphine who comes to the attention of law enforcement endangers the existence of the buprenorphine program.

 In the past I worried about prescribing Subutex, the form of the drug that doesn’t contain naloxone, or the newer generic buprenorphine, which also doesn’t contain naloxone. But apparently, some addicts are able to inject Suboxone, and the naloxone in it doesn’t put them into withdrawal. At least, they don’t go into intolerable withdrawal.

 It just shows me again that people are so different in the way they react to medications.